Tongue cancer: survival linked to white blood cell indices

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Takeaway

  • The lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) are associated with survival of patients with early oral tongue cancer.

Why this matters

  • Better prediction of patient prognosis may improve treatment stratification.

Key results

  • Low lymphocyte count (HR, 0.206; P<.001), high platelet count (HR, 1.011; P=.026), low LMR (HR, 0.721; P=.001), and high PLR (HR, 1.012; P<.001) were associated with poor DFS.
  • Low lymphocyte count (HR, 0.091; P=.01), high platelet count (HR, 1.023; P=.009), low LMR (HR, 0.58; P=.008), and high PLR (HR, 1.016; P=.002) were associated with poor OS.

Study design

  • 133 patients with pT1N0-pT2N0 oral tongue cancer were analyzed for white blood cell indices and their associations with survival outcomes.
  • Funding: None disclosed.

Limitations

  • Retrospective study from single hospital.