Breast cancer lumpectomy: fewer reoperations with neoadjuvant vs adjuvant chemotherapy

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  • Receipt of neoadjuvant chemotherapy vs receipt of postoperative chemotherapy is associated with fewer reoperations after lumpectomy for breast cancer.
Why this matters
  • Reoperation is common, with more than 1 in 5 patients treated with lumpectomy undergoing reoperation for perceived residual disease.
Study design
  • 71,627 patients with stages I-III breast cancer in the National Cancer Database (NCDB) were evaluated for type of chemotherapy and reoperation rates (RORs) using multivariable logistic regression modeling.
  • Funding: Gundersen Medical Foundation, Norma J. Vinger Center for Breast Care, University of Wiscosin La Crosse....